Scientific Vision
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Professor Andrew Millar, Co-Director At the core of our scientific vision is modelling and we seek to establish a facility for modelling which will enrich our own and others' work in systems biology. Modelling is central to systems biology, taking existing knowledge, often in the form of large datasets and through static and kinetic models, using it to generate new knowledge.
Professor Igor Goryanin, Co-Director The unique feature of CSBE is that we place this process itself at the centre of our scientific endeavour. We are uniquely placed to conduct this work. Through the work of the Centre we aim to make theoretical and practical developments to support all stages of the modelling process. Such large-scale modelling frameworks have not previously been available in the academic setting. This work will be informed by the biological projects which have been chosen to exercise all aspects of the modelling process. The modelling is supported by the Systems Biology Software Infrastructure™, a new integrated platform, facilitating the modelling process from databases to knowledge discovery. This will encompass model construction by a variety of means including graphical notation and network inference, as well as a suite of tools for model analysis including both static and kinetic analyses. On the experimental side the Kinetic Parameter Facility will provide essential data to parameterise kinetic models. |
Projects
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CSBE has close links to:
